منابع مشابه
Biofundamentals - Peptide bonds and polypeptides
Peptide bonds, polypeptides and proteins printable pdf We have already mentioned proteins, since there are few biological processes that do not rely on them. Proteins derive their name from the ancient Greek sea-god Proteus who, like your typical sea-god, could change shape. The name acknowledges the many different properties and functions of proteins. Proteins can act as catalysts and regulato...
متن کاملHow ribosomes make peptide bonds.
Ribosomes are molecular machines that synthesize proteins in the cell. Recent biochemical analyses and high-resolution crystal structures of the bacterial ribosome have shown that the active site for the formation of peptide bonds--the peptidyl-transferase center--is composed solely of rRNA. Thus, the ribosome is the largest known RNA catalyst and the only natural ribozyme that has a synthetic ...
متن کاملCovalency of hydrogen bonds in solids revisited.
The covalent nature of short hydrogen bonds has been under debate for long. Here we show that the crystal orbital Hamilton population (COHP) bonding indicator gives new, complementary evidence of covalent hydrogen···acceptor interactions in the molecular solid state.
متن کاملNatriuretic Peptide Assays Revisited
Discovery of the endocrine function of the heart (1), which exerts a fundamental role in regulating cardiovascular homeostasis through atrial natriuretic peptide (ANP) and B-type natriuretic peptide (BNP), has opened up a new field of research that has resulted in multiple clinical applications (2). The human BNP gene encodes for a pre-proBNP olecule of 134 amino acid residues, including a sign...
متن کاملEnzymatic Peptide Synthesis. Carboxypeptidase Y Catalyzed Formation of Peptide Bonds
It is demonstrated that carboxypeptidase Y from Saccharomyces cerevisiae can catalyze the formation of peptide bonds using N-acylamino acid esters as substrates and free amino acids or amino acid amides as nucleophiles, The coupling yields observed with free amino acids were max. 60 % for alanine and lysine and they depended strongly on the reaction parameters; viz. pH, temperature and concentr...
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ژورنال
عنوان ژورنال: Nature Structural & Molecular Biology
سال: 1998
ISSN: 1545-9993
DOI: 10.1038/1368